Factors Influencing the Transborder Transmission of Brucellosis in Cattle Between Côte d'Ivoire and Mali: Evidence From Literature and Current Key Stakeholders.

Brucellosis is one of the main zoonoses affecting ruminants. Cattle and small ruminants are involved in transhumance and trade between Côte d'Ivoire and Mali. The endemic nature of the disease in both countries, connected through transhumance, poses unique challenges and requires more information to facilitate disease surveillance and the development of integrated control strategies. This study aimed to assess the main factors influencing the historical and current transborder transmission of brucellosis between Côte d'Ivoire and Mali. A literature review was conducted and data collection was performed through a participatory, transdisciplinary process by holding focus group discussions and interviews with key stakeholders. Cattle breeders, herdsmen, professionals of animal and human health, border control agents and experts took part. The data was analyzed to generate essential new knowledge for transborder brucellosis transmission factors and control strategies. From the literature, the seroprevalence of brucellosis in both countries varied from 11% (1987) to 20% (2013) and 15% (1972-1973) to 5% (2012-2014) in Mali and Côte d'Ivoire, respectively. The reduction of seroprevalence in Côte d'Ivoire was the result of the annual vaccination campaigns which lowered it from 28% (1978) to 14% (1984) after an increase due to livestock policy implemented in 1976. The meta-analysis and interviews jointly showed that the cross-border mobility was associated with the livestock development policy in Côte d'Ivoire as well as the ECOWAS act on the free movement of people and goods. This act supported the seasonal transhumance of livestock for access to pasture land in southern humid zones in Côte d'Ivoire. The seasonal mobility for grazing and trade was the main risk factor for the spread of brucellosis between pastoral zones of both countries. The existing legal health framework and border control mechanism do not achieve transborder surveillance to control brucellosis. Existing sanitary regulations should be adapted at regional scale to integrate a joint surveillance of high priority zoonotic diseases like brucellosis at border controls.

Highly Pathogenic Avian Influenza A(H5N8) Virus, Democratic Republic of the Congo, 2017.

In 2017, highly pathogenic avian influenza A(H5N8) virus was detected in poultry in the Democratic Republic of the Congo. Whole-genome phylogeny showed the virus clustered with H5N8 clade 2.3.4.4B strains from birds in central and southern Asia. Emergence of this virus in central Africa represents a threat for animal health and food security.

Seroprevalence of African swine fever in Senegal, 2006.

In Senegal, during 2002-2007, 11 outbreaks of African swine fever (ASF) were reported to the World Organisation for Animal Health. Despite this, little was known of the epidemiology of ASF in the country. To determine the prevalence of ASF in Senegal in 2006, we tested serum specimens collected from a sample of pigs in the 3 main pig-farming regions for antibodies to ASF virus using an ELISA. Of 747 serum samples examined, 126 were positive for ASF, suggesting a prevalence of 16.9%. The estimated prevalences within each of the regions (Fatick, Kolda, and Ziguinchor) were 13.3%, 7.8%, and 22.1%, respectively, with statistical evidence to suggest that the prevalence in Ziguinchor was higher than in Fatick or Kolda. This regional difference is considered in relation to different farming systems and illegal trade with neighboring countries where the infection is endemic.

Seroprevalence of Neospora caninum antibodies and its consequences for reproductive parameters in dairy cows from Dakar-Senegal, West Africa.

The aim of this study was to determine the seroprevalence of Neospora caninum antibodies and its effects on reproductive parameters in cows in intensive dairy herds in Dakar. Randomised blood samples were taken for serology from 196 cows in four herds with a history of sporadic abortion. All of the sera were assayed for antibodies against N. caninum, Candida guillermondii, Coxiella burnetii, and Chlamydophila sp. The associations between serostatus and reproductive parameters (abortion, number of inseminations to conception, and calving to conception interval) were assessed over a period of 5 years (2004-2008). The seroprevalence of N. caninum antibodies in dairy cattle was 17.9%. The local Gobra breed and crossbreeds had higher levels of N. caninum antibodies than exotic breeds (p < 0.05). For the most recent pregnancies, seropositive cows required more inseminations to establish conception than seronegative cows (p < 0.05). The results indicate that dairy cattle from Dakar are exposed to N. caninum. Neosporosis should, therefore, be systematically considered as a cause when the calving to conception interval is prolonged.